Drug discovery is a complex and resource-intensive process. Traditionally, researchers have relied on trial and error, chemical intuition, and empirical methods to identify potential drug candidates. However, the advent of artificial intelligence (AI) has revolutionized this field, offering new avenues for accelerating drug discovery. Nigeria can benefit significantly from leveraging artificial intelligence in drug discovery to advance its healthcare and pharmaceutical sectors. Let’s delve into the several ways by which AI can be beneficial:
Strengthening research capacities
AI can enhance the capabilities of Nigerian research institutions by providing tools for rapid and efficient drug discovery. By integrating AI with existing research frameworks, these institutions can develop drugs more quickly and at a lower cost, focusing on diseases that are prevalent in Nigeria and Africa at large, such as malaria, tuberculosis, HIV/AIDS, and cancer.
In a significant advancement within the field of oncology, I and my team of researchers have utilized artificial intelligence to facilitate the de novo design of two novel therapeutic peptide binders, named Pep1 and Pep2. These peptides are specifically engineered to target and disrupt the interaction between MDM2 and the tumor suppressor protein p53, a pathway often implicated in cancer progression. Dysfunctional p53, which occurs in approximately 50 percent of all human cancers, plays a crucial role in tumor development and the resistance to existing treatments.
The development of Pep1 and Pep2 represents a pivotal step forward in the fight against cancer, highlighting the transformative potential of AI in drug discovery. These peptides serve as foundational components for new drug development initiatives, where further refinement and optimization could significantly amplify their efficacy and therapeutic value.
Boosting local pharmaceutical industry
AI-driven drug discovery can invigorate the local pharmaceutical industry by reducing the time and resources required to bring a drug from conception to market. This efficiency could make local companies more competitive on a global scale and reduce dependency on imported medications.
Enhancing drug repurposing
AI can identify new uses for existing drugs, potentially providing quicker access to treatments for emerging health crises without the lengthy approval process required for new drugs. This approach can be particularly valuable in managing outbreaks and addressing unmet medical needs in the Nigerian population.
Cost reduction and economic growth
By adopting AI in drug discovery, Nigeria could reduce the overall cost associated with developing new medications. Cost savings could be redirected into other vital healthcare infrastructure or services. Additionally, a robust pharmaceutical sector powered by AI could create jobs and contribute to economic growth.
Educational and skill development
Developing AI for drug discovery requires skilled personnel, providing an impetus for educational institutions to offer courses in relevant fields such as computational biology, data science, and AI. This would help build a local workforce capable of innovating within the pharmaceutical sector and beyond.
Improving healthcare outcomes
AI-driven drug discovery can lead to the development of more effective and safer drugs, improving healthcare outcomes. Personalized medicine, powered by AI, can tailor treatments to individual genetic profiles, potentially increasing the efficacy of treatments and reducing side effects.
International collaborations and investments
Establishing a strong AI-driven drug discovery sector could attract international collaborations and investments, bringing additional resources, knowledge, and technologies to Nigeria. This could further strengthen the healthcare sector and provide a boost to the local economy.
The integration of artificial intelligence (AI) into drug discovery presents a transformative opportunity for Nigeria to advance its healthcare and pharmaceutical sectors significantly. By harnessing AI, Nigeria can enhance research capabilities, invigorate the local pharmaceutical industry, expedite drug repurposing, reduce costs, foster economic growth, and improve healthcare outcomes. Furthermore, this adoption can catalyze educational advancements and skill development, positioning Nigeria as a hub for pharmaceutical innovation and attracting international collaborations and investments. Ultimately, embracing AI in drug discovery can empower Nigeria to address critical health challenges more efficiently and effectively, setting a new standard for innovation in healthcare across Africa. However, to realize these benefits, the Nigerian government would need to invest in the necessary infrastructure, provide incentives for innovation, and create policies that support the integration of AI technologies into the healthcare and pharmaceutical sectors.
Source : https://saharareporters.com/2024/08/24/revolutionizing-healthcare-how-ai-driven-drug-discovery-can-propel-nigerias#google_vignette
